BIO Bas Van Steensel

Bas Van Steensel            

Division Gene Regulation, The Netherlands Cancer Institute, Amsterdam NL  |  CV

van Steensel is Research Group Leader at the The Netherlands Cancer Institute, and Extraordinary Professor at Erasmus University Medical Centre, Rotterdam. The van Steensel lab develops and applies new genomics technologies to study the architecture and functions of chromosomes and chromatin using both Drosophila and mammalian cell lines as model systems using a broad integrative genomics approach. They conduct studies in the living cell, in the context of the entire genome. They develop and apply new genomics techniques to reveal the interplay among many chromatin proteins, to visualize the architecture of chromosomes inside the nucleus, and to detect the genome-wide effects of these factors on gene expression. They analyze the large datasets that we generate using a range of bioinformatics approaches. Recent insights from his group include the identification of four distinct classes of chromatin in Drosophila cells and the development pof techniques that allow the single cell analysis of the dynamics of genome-nuclear lamina interactions and chromatin position effects.

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