BIO Marius Wernig

Marius Wernig

Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford US  |  CV

The Wernig lab at Stanford University School of Medicine is working on the epigenetic regulation of stem and somatic cells, with a particular interest in the mechanisms that determine cell fate identity. Their focus is on epigenetic reprogramming to induce cell fate changes by defined factors, such as the reprogramming of somatic cells into pluripotent stem (or iPS) cells. In particular, their lab has developed new methods to generate iPS cells from human fibroblasts, and is exploring various technologies to improve gene targeting in human iPS cells with a long term goal to correct disease-causing mutations. In addition, in a recent seminal study from the group, they identified defined factors that induce the direct conversion of skin fibroblasts into functional neurons, opening up new avenues for study for disease modeling and regenerative medicine.

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